The Journal of Bucharest College of Physicians and the Romanian Academy of Medical Sciences

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Saturday, August 27 2016 @ 06:06 EEST

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Carcinosarcoma of the Uterine Corpus - a Case Report and Brief Review of the Literature

2016-02

Tiberiu Augustin Georgescu, Monica Cirstoiu, Florin Catalin Cirstoiu, Mariana Costache, Anca Lazaroiu, Adrian Dumitru, Maria Sajin

Malignant Mixed Müllerian Tumors (MMMT) also referred to as carcinosarcomas are very rare and extremely aggressive tumors of the uterine corpus accounting for less than 1% of all gynecologic malignancies, 2-5% of all uterine malignancies and more than 15% of all uterine cancer associated deaths [1]. They occur almost exclusively in post-menopausal women, but have been reported in premenopausal women as well, including young girls [2]. Carcinosarcomas have poor prognostic outcome, regardless of stage at diagnosis. The five-year survival rate ranges between 5% and 40% for patients with tumors of all stages [2-5] and does not improve significantly even with the introduction of increasingly aggressive adjuvant therapies.

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A Rare Tumor - Primary Leiomyosarcoma of Pulmonary Artery. Case Presentation

2016-02

Laura Rebegea, Dorel Firescu, Mihaela Dumitru, Alina Mihaela Calin, Rodica Anghel

Pulmonary artery sarcomas (PA) are uncommon; the first case was documented in 1923 by Mandel Staam. Leiomyosarcoma, fibrosarcoma and rhabdomyosarcoma are the most often histologically confirmed incidences. PA tumor is frequently misinterpreted as thrombo-embolism, as its correct diagnosis is difficult. Magnetic Resonance Imaging (MRI) is superior in providing an accurate diagnosis. Surgery is the only therapeutic strategy which may extend life expectancy. The survival rate in the absence of surgical care is of 1.5 months, survival for 5 years - 6%. In most cases, death occurs by heart failure, and rarely by distant metastases. [...]

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Urinary System Spontaneous Rupture - an Urological Emergency

2016-02

Dragos Marcu, Ovidiu Bratu, Dan Spinu, Robert Popescu, Agnes Ciuca, Maria Galaman, Ioana Oprea, Dan Mischianu

Spontaneous rupture of the urinary collecting system is a rare urologic pathology, but due to the severity of its possible complications, it represents an urological emergency which requires adequate urgent treatment. [...]

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The Role of the Extraperitoneal Drainage in the Corrective Surgery of the Intraoperative-Discovered Accidental Lesions of the...

2016-02

The Role of the Extraperitoneal Drainage in the Corrective Surgery of the Intraoperative-Discovered Accidental Lesions of the Common Bile Duct

Alec Cosmin Moldovan, Florin Dan Ungureanu, Vladimir Belis

Up to date, one of the most well-known and used classification for defining bile duct lesions belongs to Bismuth [1] and was later assumed by laparoscopic surgery as well. In this classification, the author is taking into consideration the remaining intact bile duct length and does not include bile collections that may arise from a bilistasis defect in the cystic duct or the liver bed, nor the lateral solutions of continuity of the main bile duct and right hepatic duct. These kind of iatrogenic injuries were initially reported only after classic cholecystectomy, and this is why, later, with the development and rise of the laparoscopic approach, Strasberg and Soper [2] modified this classification of accidental injuries inclu-ding these as well. [...]

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Pharmacodynamics of Serotonin. Emphasis on 5HT-3 Antagonists and SSRI Medication (I)

2016-02

Mihnea Costescu, Horia Paunescu, Sorina Vasile, Aurelian Zugravu, Oana Andreia Coman, Ion Fulga

Serotonin (5-hydroxytryptamine or 5-HT)is a mo-noamine neurotransmitter involved in regulating and modulating physiological and behavioral processes [1]. Serotonin also plays an important role in the functio-ning of enteric nervous system [2]. [...]

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