The Journal of Bucharest College of Physicians and the Romanian Academy of Medical Sciences

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Friday, August 18 2017 @ 05:25 EEST

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A Curious Case of Rhinophyma in a 73-Year-Old Patient

2017-02

Tiberiu Paul Neagu, Khalid Al-Falah, Mirela Tiglis, Iulia Gabriela Marcu, Cristian Radu Jecan, Liliana Elena Mirea, Ioan Lascar

Rhinophyma is a benign tumor characterized by a pro-gressive hypertrophy of the nose soft tissues, with a re-ddish and bulky appearance, affecting most frequently elderly Caucasian males[1], which may also cause functional airway obstruction. It is believed to be the end stage of severe acne rosacea, but the real cause and the exact etiology remain unknown[1]. The male to female ratio of rhinophyma patient varies between 5 to 1 and 30 to 1 [2,3]. The diagnosis is based on the clinical features of this rare and disfiguring disease using Rhinophyma Severity Index Score (RHISI)[4]. The main differential diagnosis is the basal cell carcinoma (BCC), with an occult incidence of 3% to 10% in patients with rhinophyma[1]. [...]

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Prenatal Diagnosis and Genetic Counselling in Turner Syndrome: Case Report and Literature Review

2017-02

Viorica Tudor, Octavia Velicu, Mihai Mitran, Elvira Bratila, Emilia Severin

The first paper describing female patients with Turner syndrome (TS) was published in 1938 by Henry Turner[1]. It was later discovered that in 1930, Otto Ullrich had already reported a case report of a girl with suggestive symptoms of TS[2]. Therefore, the complete name is Ullrich-Turner syndrome.

Turner’s syndrome is a pathology found only in females, characterized by the partial or total absence of a second sex chromosome which leads to a wide range of physical findings that often includes congenital lymphedema, short stature, and gonadal dysgenesis[1]. The physical symptoms depend on the karyotype, as only 50% of Turner patients are 45,X the others displaying mosaics or abnormalities in the second sex chromosome. [...]

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Cardiotoxicity of Multimodal Treatment for Breast Cancer

2017-02

Radu Valeriu Toma, Georgia Luiza Serbanescu, Mihail Alexandru Oprea, Rodica Maricela Anghel

In the era of the optimal and the personalized oncological treatments, life expectancy increases, therewith the need of understanding and managing side effects is a challenging task.

The most notable research advances in breast cancer involve new radiation treatments techniques and targeted therapies.

Cardiac toxicity following radiotherapy (RT) is recognized as an important issue. Furthermore, with the prevalent and necessary treatment with anthracyclines and trastuzumab, which carry an independent and confirmed risk of cardiotoxicity[1-3] the additional heart disease risk following radiotherapy must be kept to a minimum. [...]

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Charcot Foot Diagnosis - Still an Issue?

2017-02

Ion Cocolos, Tiberiu Paul Neagu, Andrei Tudor Ursache, Ioan Cristescu, Mircea Vasile Ghemigian, Liliana Elena Mirea, Gheorghe Ion Popescu

The Lisfranc fracture-dislocation of the foot is uncommon and many cases are misdiagnosed. The Lisfranc lesion involves the medial cuneiform and base of the second metatarsal which are considered to be the keystone of the structural integrity of the midfoot. This joint has a stabilization effect on longitudinal and transverse arches of the foot. A neglected or untreated injury to the Lisfranc joint can lead to secondary arthritis and significant morbidity with disability. Furthermore, it is well known the correlation between pacients with periferic neuropathy and this type of lesion, also known as Charcot Foot[1]. It has been documented to occur as a consequence of various peripheral neuropathies, but diabetic neuropathy has become the most common etiology[2]. [...]

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A Retrospective on the Treatment of Trochanteric Fractures of the Femur in the Bucharest Clinical Emergency Hospital in 2015

2017-02

Fabian Klein, Ioan Cristescu, Florin Safta, Daniel Vilcioiu

Fractures of the proximal femur are some of the most commonly encountered fracture types, especially when talking about elderly patient[1,2]. Apart from the immediate impact on the patient’s health, a more problematic issue is the impact on the quality of life, especially when talking about geriatric patients[3]. Early surgical treatment, combined with early discharge from hospital and a well-tailored rehabilitation program are mandatory for assuring a quick recovery of the patient’s autonomy. It is estimated that every person over the age of 65 has a 10% chance to fall once per year, with the possibility of contracting a proximal femur fracture. [...]

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