The MODERN MEDICINE - MEDICINA MODERNA is Indexed by EBSCO and Index Copernicus
CNCS B+ Category Journal
CME Credits: 10 (Romanian College of Physicians)
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Str. Avram Iancu Nr. 1, Sect. 2
Bucuresti, Romania

Current issue

Nr. 1/2015, Vol. 22

A New Step

in Sharing Medical Experience

Medicina ModernĂ£

New Series

NBI Guided TURBT in NMIBC Management – “The Right Path” to Better Tumor Ablation

B. Geavlete, C. Ene, C. Bulai, I. Al. Checheriţă, P. Geavlete

Introduction & Objectives: The standard bladder cancer management was often marked by unsatisfactory outcomes. This prospective, single-center study compared the diagnostic accuracy specific for narrow band imaging (NBI) and respectively white light cystoscopy (WLC) among non-muscular invasive bladder cancer (NMIBC) patients.
Materials & Methods: 81 consecutive NMIBC suspected cases were included based on the presence of hematuria and or on ultrasound suspicious aspect. All patients were evaluated by both WLC and NBI cystoscopy. WL-visible lesions were removed by classical transurethral resection of bladder tumors (TURBT), while NBI resection…[more...]

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Presence of p53 in Tumor Cells – an Indicator of Disease Severity?Retrospective Study in Patients with NSCC (Partial Results)

Antonela Dragomir, M. Alexe, Diana Leonte, Florina Vasilescu, Daciana Marta

The lung cancer is the most common malignancy followed by cancers of breast, prostate and colon. The cancerous cells contain many genetic aberrations that occur throughout the cell cycle. The mutant protein and its investigation might provide insight into the molecular and histological characteristic of the disease. This retrospective study we established 40 patients selected conform inclusion and exclusion criteria froAm hospitalized people. All patients has been investigated with a succession of investigations (X-ray, bronchoscopy, computed tomography, biopsy), up to histology and immunohistochemical determinations.
Among the markers used i…[more...]

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IPSS Score and IL-6 Before and During Treatment with Dutasteride in Patients with Benign Prostatic Hyperplasia

C.V. Ene, Corina Daniela Ene, Ilinca Nicolae, B. Geavlete, Oana Andreia Coman

Introduction: Benign prostatic hyperplasia is one of the most common pathologies in aging men, associated with lower urinary tract symptoms.
Objective: Evaluating the relation between clinical status (IPSS score – International Prostatic Symptom Score) and the IL-6 serum values in patients with benign prostatic hyperplasia before and during medical treatment with dutasteride.
Material and methods: This is a clinical prospective-observational study, which included 35 adult males diagnosed with benign prostatic hyperplasia. The patients were evaluated at the beginning of the treatment with dutasteride 0.5 mg daily (Moment 0), and at 6 months (M…[more...]

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Ultrastructural Arguments for the Extracellular Location of Amyloid Deposits

E. Mandache, M. N. Penescu

Objectives: Amyloidosis is a disease characterized by the occurrence of small and large deposits containing a fibrillar material of insoluble proteins, which is lately more and more frequently identified due also to electron microscopy. The pathogeny and mechanisms of amyloidosis have still many question marks. Most people consider the amyloid deposits as interstitial accumulations. Some authors are still considering formation of amyloid collections both intra and extracellular.
Methods: To assume a definite opinion in this matter we have investigated carefully with the electron microscope, the occurrence of amyloid fibrillar material in atri…[more...]

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SIRS and MODS in Acute Pancreatitis

C.C. Popa, Octavia Cristina Rusu, Alexandra Kocsis, S.I. Neagu, C.R. Strugaru

Acute pancreatitis is a serious illness characterized by acute inflammation of the pancreatic acinar gland cells.
Loss of local control or exaggerated inflammation will cause an inflammatory response of the body that can be of two kinds: systemic pro-inflammatory response syndrome or compensatory anti-inflammatory response syndrome. The imbalance caused by the influences of two types of body responses produces numerous serious clinical and biological consequences. In the final stage of the disease, due to inefficient or excessive compensatory anti-inflammatory reaction, immunosuppression and multiple organ dysfunction (MODS) with increased mo…[more...]

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