The Journal of Bucharest College of Physicians and the Romanian Academy of Medical Sciences

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Sunday, November 18 2018 @ 04:48 EET

Botulinum Toxin Type A - Possible Anti-Nociceptive Effect on Mice


Elena-Rodica Dragu, Bogdan Liviu Chioaru, Ioana Teona Sebe, Ioan Lascăr, Oana Andreia Coman

Botulinum neurotoxin has been used in the treatment of various groups of cronic neuromuscular diseases, which include neuromuscular junction signaling, non-neuromuscular transmission, cholinergic, or non-cholinergic.

Having specificity on releasing neurotransmitter vesicles with acetylcholine in the synaptic gap, the main usage of botulinum toxin was as a muscle relaxant drug in painful or painless spastic syndromes.

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