The Journal of Bucharest College of Physicians and the Romanian Academy of Medical Sciences

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Sunday, November 18 2018 @ 04:50 EET

Genome-Wide Association Scan for Variants Associated with Early-Onset Prostate Cancer in Romania


George Daniel Radavoi, Paul Daniel Iordache, Viorica Radoi, Radu Ioan Ursu, Stefan Rascu, Cristian Sima, Marian Vargau, Bogdan Cheorpeaca, Dan Mischianu

Prostate cancer incidence varies more than 25-fold worldwide, largely due to the widespread practice of prostate specific antigen (PSA) testing and subsequent biopsy [1]. It is the second most frequently diagnosed cancer of men (914.000 new cases per year, accounting for 13.8% of total cancer cases) and the 5th most common cancer overall worldwide. The incidence is expected to grow to 1.7 million new cases and 499.000 deaths by 2030, mainly due to the growth and aging of the global population [2]. [...]

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