The Journal of Bucharest College of Physicians and the Romanian Academy of Medical Sciences

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Wednesday, November 21 2018 @ 12:22 EET

Carcinosarcoma of the Uterine Corpus - a Case Report and Brief Review of the Literature


Tiberiu Augustin Georgescu, Monica Cirstoiu, Florin Catalin Cirstoiu, Mariana Costache, Anca Lazaroiu, Adrian Dumitru, Maria Sajin

Malignant Mixed Müllerian Tumors (MMMT) also referred to as carcinosarcomas are very rare and extremely aggressive tumors of the uterine corpus accounting for less than 1% of all gynecologic malignancies, 2-5% of all uterine malignancies and more than 15% of all uterine cancer associated deaths [1]. They occur almost exclusively in post-menopausal women, but have been reported in premenopausal women as well, including young girls [2]. Carcinosarcomas have poor prognostic outcome, regardless of stage at diagnosis. The five-year survival rate ranges between 5% and 40% for patients with tumors of all stages [2-5] and does not improve significantly even with the introduction of increasingly aggressive adjuvant therapies.

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