The Journal of Bucharest College of Physicians and the Romanian Academy of Medical Sciences

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Monday, December 10 2018 @ 06:39 EET

The Effect of Allopurinol on Endothelial Function, Serum Uric Acid and NT-proBNP in Acute Decompensated Heart Failure


Madalina Sorina Ababei, Alexandru Campeanu, Diana Cornelia Nistorescu, Ondin Zaharia, Gabriela Gheorghe, Ileana Peride, Andrei Niculae, Ioan Tiberiu Nanea

Acute decompensated heart failure has an increasing incidence and poor prognosis, being a major cause of death and hospital readmission and requiring urgent optimized therapy[1]. Under the influence of some decompensation risk factor, such as infections, arrhythmias, decompensation of some comorbidities, lack of adherence to the treatment, patients with a history of heart failure may suffer a progressive symptomatology worsening; therefore, more than 70% of cases of acute heart failure represent the clinical worsening of chronic heart failure - ADHF[2]. [...]

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