The Journal of Bucharest College of Physicians and the Romanian Academy of Medical Sciences

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Wednesday, November 21 2018 @ 12:21 EET

The Effect of Timolol on the Iris Vascular Tone in Rats


Dragos-Constantin Lunca, Horia Paunescu, Mihnea Costescu, Laurentiu Coman, Ion Fulga

Vascular tone is generally controlled by both the humoral component and the neuro-vegetative component. Regarding the second one, catecholaminergic sympathetic innervation of blood vessels is almost a rule in the body[1,2].

It is known that the iris is sympathetically inner-vated, both at the level of the iris dilator muscle[1,2] and at the level of iris blood vessels[3]. Cathecolamines are responsible for vasoconstriction and, in some vascular beds, vasodilation. [...]

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