The Journal of Bucharest College of Physicians and the Romanian Academy of Medical Sciences

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Monday, October 23 2017 @ 05:28 EEST

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How Can the Number of Diseased People Be Reduced in General by Implementing One Health Concept (ONE HEALTH WHITE BOOK)

2017-03

Nicolae Manolescu, Mircea Ifrim

From our point of view, the living environmentrefers to the sum total of events that take place around-the-clock in a living area that includes the soil alongside air, and water, including all living creatures(plants, animals and humans), plus the invisible worldthat causes di-seases in humans and animals, consisting of both biotic factors(bacteria, viruses, fungi and parasites) and abiotic factors(toxic and oncogenic chemicals). [...]

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Penile Neoplasia Forensic Approach

2017-03

Dan Spinu, Catalin Belinski, Ioana Oprea, Dragos Marcu, Dan Mischianu, Ovidiu Bratu

Penile cancer is a relatively rare neoplasia with the overall incidence of less than 1 from 100000 patients in Europe and USA[1,2]. The majority of them are common scuamous cell carcinoma 48-65% of the cases followed by basaloid carcinoma, warty carcinoma, verrucous carcinoma, papillary carcinoma which cover for more than 30% with the rest of 5% going to rare types of neoplasia or mixed types.

As in cervix carcinoma the role of HPV has been proved, infact there is a rare type of PC which is directly linked to HPV[3]. As such, the prevalence of penile neoplasia is related to that of HPV in general population. Strains 16 and 18 are the most common findings in penile carcinoma[4]. [...]

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A Curious Case of Rhinophyma in a 73-Year-Old Patient

2017-02

Tiberiu Paul Neagu, Khalid Al-Falah, Mirela Tiglis, Iulia Gabriela Marcu, Cristian Radu Jecan, Liliana Elena Mirea, Ioan Lascar

Rhinophyma is a benign tumor characterized by a pro-gressive hypertrophy of the nose soft tissues, with a re-ddish and bulky appearance, affecting most frequently elderly Caucasian males[1], which may also cause functional airway obstruction. It is believed to be the end stage of severe acne rosacea, but the real cause and the exact etiology remain unknown[1]. The male to female ratio of rhinophyma patient varies between 5 to 1 and 30 to 1 [2,3]. The diagnosis is based on the clinical features of this rare and disfiguring disease using Rhinophyma Severity Index Score (RHISI)[4]. The main differential diagnosis is the basal cell carcinoma (BCC), with an occult incidence of 3% to 10% in patients with rhinophyma[1]. [...]

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Prenatal Diagnosis and Genetic Counselling in Turner Syndrome: Case Report and Literature Review

2017-02

Viorica Tudor, Octavia Velicu, Mihai Mitran, Elvira Bratila, Emilia Severin

The first paper describing female patients with Turner syndrome (TS) was published in 1938 by Henry Turner[1]. It was later discovered that in 1930, Otto Ullrich had already reported a case report of a girl with suggestive symptoms of TS[2].†Therefore, the complete name is Ullrich-Turner syndrome.

Turnerís syndrome is a pathology found only in females, characterized by the partial or total absence of a second sex chromosome which leads to a wide range of physical findings that often includes congenital lymphedema, short stature, and gonadal dysgenesis[1]. The physical symptoms depend on the karyotype, as only 50% of Turner patients are 45,X the others displaying mosaics or abnormalities in the second sex chromosome. [...]

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Cardiotoxicity of Multimodal Treatment for Breast Cancer

2017-02

Radu Valeriu Toma, Georgia Luiza Serbanescu, Mihail Alexandru Oprea, Rodica Maricela Anghel

In the era of the optimal and the personalized oncological treatments, life expectancy increases, therewith the need of understanding and managing side effects is a challenging task.

The most notable research advances in breast cancer involve new radiation treatments techniques and targeted therapies.

Cardiac toxicity following radiotherapy (RT) is recognized as an important issue. Furthermore, with the prevalent and necessary treatment with anthracyclines and trastuzumab, which carry an independent and confirmed risk of cardiotoxicity[1-3] the additional heart disease risk following radiotherapy must be kept to a minimum. [...]

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