The Journal of Bucharest College of Physicians and the Romanian Academy of Medical Sciences

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Monday, October 23 2017 @ 05:32 EEST

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Protocol for Fat Tissue Manipulation in Regenerative Treatment for Bilateral Coxarthrosis in Dogs

2016-01Dana Jianu, Gabriel Predoi, Iuliana Ionascu, Oltjon Cobani, Stefan Jianu, Andreea Nita, Mircea Ifrim

Hip dysplasia commonly leads to osteoarthrosis of the hip joint (coxarthrosis) and these two diseases are two of the most frequently encountered problems in veterinary practice. The available treatment modalities are varied and range from drugs to alleviate pain and inflammation to surgical techniques, such as hip replacement, and various physical therapy measures.

The research regarding therapy using adipose derived stem cells (ADSC) in veterinary medicine, started in 2002. Advances in understanding of the biology of adult stem cells have attracted the attention of the biomedical research community, including those studying osteoarthritis. (1) Autologous adult stem cells are immunologically compatible, can be harvested from a variety of sources, including bone marrow and adipse tissue (1), and have no ethical issues related to their use [...]

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External Postoperative Biliary Lithiasic Fistulae Associated with Choleperitoneum

2016-01Alec Cosmin Moldovan, Laurentiu Ungurianu, Mihaela Pricop, Mirela Debretin, Toba Madalina, Florin Dan Ungureanu, Vladimir Belis

Laparoscopic cholecystectomy is regarded as a safe procedure, which could allow only with great difficulty the possibility of unpleasant progression or intraoperative surprises [2]. Both findings are now able to allow in most cases an optimal therapeutic conduct and a most simple postoperative evolution, devoid of consequences.

But, however, even with diagnosis establishment and surgical indication with maximum precision, such as a very advanced surgical technique, surgery further reserves the right to not always provide nor pleasant, nor easy to solve surprises [...]

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Metachronous Cancers

2016-01Matei Bara, Georgia-Luiza Serbanescu, Toma Radu Valeriu, Rodica Anghel

According to GLOBOCAN, cervical cancer is the fourth most common cancer worldwide touching woman, with approximately around 500000 new cases and 266000 deaths in 2012; in Romania, cervical cancer is the second malignancy diagnosed in women. Cervical cancer is responsible for 7.5% from the whole female cancer deaths and 87% of these cases are encountered in the less developed regions of the world.

The more advanced is the stage of cervical cancer, the worse the prognosis is and the treatment in these cases is mainly palliative with an average survival period of only 7 years as observed in recurrent and/or metastatic cancer [...]

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Lipoma of the Proximal Forearm with Compression of the Superficial Radial Nerve

2016-01Roxana Maria Enescu, Alexandru Ioan Tomek, Marius Popescu, Ioan Lascar

Compressive neuropathies in the upper limb represent a common and admittedly more and more frequent pathology, given how certain peripheral nerves posess an inherent risk of becoming injured due to anatomical positioning. [14] Obesity rate increase and the ageing of population altogether suggest that compressive neuropathies in the upper limb will become even more frequent in the next decade. [14] The most common sign of nervous compression is the carpal tunnel syndrome, prevailing in approximately 3% of the general population, followed by the cubital tunnel syndrome, and finally the radial tunnel syndrome, which is quite rare. [9] [...]

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Worsening Renal Function in Elderly Patients with Heart Failure and Chronic Kidney Disease: An Update

2016-01Alice Balaceanu, Carmen Bogeanu, Razvan Dragomirescu, Camelia Diaconu, Gheorghita Aron, Ion Dina

Chronic kidney disease (CKD) is defined as either kidney damage or eGFR (estimated glomerular filtration rate) < 60 mL/min/1.73 m2 for three or more months [1]. Elderly patients have often an impaired basal renal function due to intrinsic renal disease or to a physiological decrease in the number of functional nephrons [2]. Half of adults over the age of 70 years have eGFR < 60 mL/min/1.73 m2 [3]. CKD occurs in about 4.5% of the general population and 50% in patients with chronic or acute heart failure (HF) [4]. Commonly, CKD can be associated with chronic heart failure in elderly patients [2] [...]

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Metabolic Syndrome - Cardiovascular and Metabolic, Complex, Difficult to Quantify Risk Factor

2016-01Radu-Valentin Coltuc, Victor Stoica

MS is a clinical and pathological entity, characterized by a cluster of related clinical, anthropometric and biochemical features such as abdominal obesity, hyperglycemia, dyslipidemia and hypertension. (1) The importance of MS results from the fact that its component factors increase cardiovascular risk (2), are a strong predictor of occurrence of type 2 diabetes (3), generate fatty liver (4) and also increase all-cause mortality. (5) [...]

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The Role of Echocardiography in the Surgical Management of Secondary Mitral Regurgitation

2016-01Sebastian Onciul, Vlad Vintila, Maria Dorobantu

Secondary mitral regurgitation (MR) also known as functional mitral regurgitation is more common, portends a worse prognosis than primary MR and its management is more difficult and less sustained by evidence. [1]The etiology of secondary MR may be ischemic or nonischemic such as in idiopathic dilative cardiomyopathy. The prognosis of patients with secondary MR is worse with increasing severity of MR.[2]

The mechanism of secondary MR is linked to the left ventricle (LV) geometrical remodeling with secondary tethering of the mitral leaflets, while the valve morphology is normal. [3][4] [...]

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Familial Isolated Pituitary Adenomas

2016-01Ionela Baciu, Serban Radian, Catalina Poiana

Pituitary adenomas (PAs) are the most frequent cause of cranial tumors [1,2], benign by histology but with high morbidity caused by their complications – hypersecretion of pituitary hormones but also compression of surrounding structures thus affecting the visual field or causing pituitary deficiency. Their etiology, although intensely studied in the last 30 years, is still largely unknown.

The natural evolution and the response to current treatment options of PAs (surgery, medication and radiotherapy) are very variable, influenced by various factors, some identified and some still to be found. Early diagnose and treatment is associated with better prognosis thus identifications of patients at risk for developing a PA and targeted follow-up would result in a better management of the disease [...]

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Integrated Multidisciplinary Diagnostic Service Using a Telemedicine Platform

2016-01Andrei Manu-Marin

The term of telemedicine involves the use of medical information sent between two or more sites via electronic communication means, having as an ultimate goal the improvement of patients’ clinical condition. After already four decades of development and practical use of this diagnostic and treatment modality, with demonstrations in hospitals extending their remote healthcare services, the use of telemedicine extended rapidly, now being integrated in different current operations in hospitals, specialty departments, home care agencies, private practice offices, and also in different workplaces or residential sites, benefiting nowadays of a variety (constantly increasing) of applications and services using bi-directional video broadcasts, e-mail services, smart phones, wireless devices and other forms of telecommunication technology. (1,2) [...]

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Importance of Nutritional Status in Treatment Response of Patients with Nasopharyngeal Carcinoma

2016-01Cristina Sanda, Irina Radu, Bogdan Popescu, Maria Alexandra Barbu, Codrut Sarafoleanu, Cornelia Nitipir

Nasopharyngeal carcinoma (NPC) is the most frequent type of malignant tumor of nasopharynx. It represents 2% of all upper aero-digestive tract cancers (1). There is no uniform geographic spread of NPC with the highest rate in Southern China (Guangdong Region) 20-50/100.000 inhabitants, then South-Eastern Asia, Eskimos population, Northern Africa and Middle East.

The incidence is higher in male gender than in women with a ratio of 2-3:1 (2). It has been observed in both high and low incidence areas [...]

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