The Journal of Bucharest College of Physicians and the Romanian Academy of Medical Sciences

Welcome to ModernMedicine
Wednesday, November 21 2018 @ 12:21 EET

View Printable Version

Another Onset Mode for Rheumatoid Arthritis: Emergency Lab, Ultrasound or Both? Case Report and Literature Review

2017-04

Alice Balaceanu, Adriana Diaconu, Adriana Stanica, Camelia Diaconu

https://doi.org/10.31689/rmm.2017.24.4.214

Rheumatoid arthritis is a systemic autoimmune disease, with complex etiology and multiple genetic, immunologic, hormonal factors[1]. The onset could be insidious, like in the most patients or acute, with synovitis and extra-articular manifestations, encountered in 10% of patients[1].

We report a case of a 41 years old woman, non-smoker, without medical history, who complains about inter-mittent leg pain for 2 months, initially left calf, than bilateral, with edema in the both ankle and calf. The patient denied trauma. She is referred to emergency department for deep vein thrombosis suspicion [...]

View full article
View Printable Version

Hypospadias - the Surgical Treatment Performed in "Grigore Alexandrescu" Emergency Clinical Hospital for Children

2017-04

Laura Niculescu, Catalin-Ion Chiriac-Babei, Andra Rusalim

https://doi.org/10.31689/rmm.2017.24.4.209

Hypospadias represents one of the most frequent con-genital anomalies, in 1 out of 300 male newborns, involving significant biological and socioeconomical implications. Furthermore, recent studies show an increase in its incidence, even after ajusting it according to race, geographic region or socioeconomical status[3]. The same pattern was recorded by the EUROCAT study group, which was monitoring the statistical and epidemiological data regarding the congenital anomalies in Europe. One prospective study, which evaluated the incidence of the hypospadias in Holland (0.7%), demonstrated that it is more frequent than congenital heart anomalies (0.5%), which are considered to be the most frequent ones by the EUROCAT study group[5]. [...]

View full article
View Printable Version

Essential Aspects in Ensuring the Efficient Management of Ovarian Tumors in Children in Case of an Acute or Chronic Setting

2017-04

Catalin Ion Chiriac-Babei, Andra Rusalim, Adham Charkaoui, Razvan Constantin Datu

https://doi.org/10.31689/rmm.2017.24.4.204

Considering the unspecific signs and symptoms asso-ciated to ovarian tumors, a proper diagnostic procedure must be followed in order to establish the most suitable therapeutic approach. Furthermore, there is no correlation between the clinical presentation of the patient and the type of ovarian tumor which is causing it. Consequently, the imagistic examination of the patient is crucial in the diagnostic process, but it is not infallible. This study is attempting to emphasize the main differences between the imagistic features of the ovarian tumors compared to the ones discovered intraoperatively, as well as the associated conditions which could prevent getting a proper preoperative diagnosis. [...]

View full article
View Printable Version

Radionuclide Imaging. An Update on the Use of Dynamic Renal Scintigraphy

2017-04

Raluca Mititelu, Ovidiu Bratu

https://doi.org/10.31689/rmm.2017.24.4.199

Renal scintigraphy is a nuclear medicine technique that uses medical radioactive isotopes for the evaluation of the renal function. Functional data complete clinical and anatomical data obtained through other imaging techniques and can assist the clinician in the diagnostic and management of various renal disorders.

The most widely used radioactive isotope for me-dical imaging is Technetium-99m. In renal scintigraphy 99m-Tc is coupled to a substance that is eliminated predominantely by glomerular filtration (DTPA) or tubular excretion (MAG3) or which is attached to tubular proteins (DMSA). DTPA and MAG3 allow a dynamic study which result in the generation of a nephrographic curve for each kidney and the calculation of clearance parameters - ie glomerular filtration rate (GFR) or the effective renal plasma flow (ERPF), respectively. [...]

View full article
View Printable Version

The Impact of Testicular Cancer on Fertility - Literature Review

2017-04

Vasilica Minciuna, Octavian Cretu, Dan Spinu, Dragos Marcu, Ovidiu Bratu

https://doi.org/10.31689/rmm.2017.24.4.195

Testicular cancer has an increased incidence among young males (15-35 years old)[1].

The incidence in testicular cancer for this category of patients is quite high, 7.52 new cases for 100000 people. The predominant histopathological subtypes among fertile-aged young males are embryonal carci-noma and teratocarcinoma[1]. [...]

View full article
View Printable Version

The Diagnosis of Urological Neoplasm in Dialysis Patients - a Brief Review

2017-04

Mircea Merticariu, Andrei Niculae, Corina-Ioana Merticariu, Ileana Adela Vacaroiu, Flavia Liliana Turcu, Viorel Jinga

https://doi.org/10.31689/rmm.2017.24.4.190

The ideea of this review arised from a small lot of patients recently evaluated by a joint team of urologists and nephrologists in one of the largest dialysis departments in Bucharest, Romania. We decided to review the existing medical literature in order to have a better grasp of the peculiarities regarding the incidence, symptoms, tumor markers and imaging studies for urological cancers in end stage renal disease (ESRD) patients undergoing dialysis. [...]

View full article
View Printable Version

Important Aspects to Take Into Consideration When Administering Cytotoxic Chemotherapy. A Review

2017-04

Cornelia Nitipir, Ana-Maria Popa, Pompilia Motatu, Bogdan Popescu, Cristian Iaciu, Mihaela Olaru, Anca-Mihaela Pantea Stoian, Razvan Hainarosie, Silviu Pituru, Maria Barbu

https://doi.org/10.31689/rmm.2017.24.4.185

In the last decade, huge efforts have been made to optimize and personalize oncological treatment. Many novel therapies and better combinations of older ones have been implemented. Even if novelty is always exciting, one has take into consideration that the way a drug is administered is as important as the drug itself. The present review focuses on how the administration of several cancer drugs can minimize the toxicity they induce. It stresses that if enough importance is given to this aspect, patients can tolerate effective doses of treatment with better outcomes and have better quality of life. [...]

View full article
View Printable Version

Relevance of Genotyping for the Clinical Management, Transmission and Control Programs of Tuberculosis

2017-04

Olimpia Nicolaescu

https://doi.org/10.31689/rmm.2017.24.4.177

More than 130 years after the discovery of its causative agent, TB still produces nearly 9 million new infections and 1.5 million deaths every year (one-quarter among them are patients co-infected with human immunodeficiency virus - HIV)[1]. Th eincidence of TB ranges from less than 10 per 100.000 in North America to 100 - 300 per 100.000 in Asia and Western Russia, to over 300 per 100.000 in Southern and Central Africa. In several regions of the world, the rise of incidence is linked to the increasing impact of HIV epidemics, drug resistant TB and deficiencies of current TB control programs. Th ese reasons determined WHO to declare TB a global emergency in 1993[2]. [...]

View full article